C beam: Monte Carlo simulations and experiment

نویسندگان

  • Linh T. Tran
  • David Bolst
  • Susanna Guatelli
  • Dale A. Prokopovich
  • Ying Chee Keat
  • Michael L. F. Lerch
  • Marco Petasecca
  • Mark I. Reinhard
  • Eleni Sagia
  • Alberto Fazzi
  • Andrea Pola
  • Stefano Agosteo
  • Naruhiro Matsufuji
  • Anatoly B. Rosenfeld
چکیده

Charge particle therapy with 12 C ions has the advantage of an enhancement in physical dose distribution due to the Bragg Peak (BP) related to higher Relative Biological Effectiveness (RBE) with respect to X-ray radiotherapy and proton therapy (2.5 for 12 C ions and 1.1 for protons) [1], [2]. The RBE of a 12 C therapeutic beam changes dramatically with depth, especially towards the end of the Spread Out Bragg Peak (SOBP), due to very high Linear Energy Transfer (LET) of the 12 C ions in this region. Additional complexity in the determination of the RBE is associated with the nuclear fragmentation process which leads to the production of lighter charged ions, with lower LET, and neutrons. Therefore, it is important to derive the RBE as well as study the fragments contribution of a therapeutic 12 C beam at the BP and SOBP.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of dose distribution of 12C ion beam in radiotherapy by FLUKA as a Monte Carlo simulation Code

Introduction: Nowadays, the use of heavy ion beams in cancer therapy have been developed worldwide.   Materials and Methods: It requires accurate understanding of the complex processes of ion interaction with matter, as it is the calculation the relative dose & range of these ions in matter. In the present study we used FLUKA as a numerical Monte Carlo simula...

متن کامل

Benchmarking of Monte Carlo model of 6 Mv photon beam produced by Siemens Oncor® linear accelerator: determination of initial electron beam parameters in comparison with measurement

Introduction: The aim of this study was to investigate the initial electron beam parameters for Monte Carlo model of 6MV photon beam produced by Siemens Oncor® linear accelerator.   Materials and Methods: In this study, the EGSnrc Monte Carlo user codes BEAMnrc and DOSXYZnrc were used. The beamnrc code were used for modelling of a 6 MV photon beam produced by...

متن کامل

Secondary Particles Produced by Hadron Therapy

Introduction Use of hadron therapy as an advanced radiotherapy technique is increasing. In this method, secondary particles are produced through primary beam interactions with the beam-transport system and the patient’s body. In this study, Monte Carlo simulations were employed to determine the dose of produced secondary particles, particularly neutrons during treatment. Materials and Methods I...

متن کامل

Comparison of measured and Monte Carlo calculated dose distributions from “circular collimators” for radiosurgical beams

Background: Stereotactic radiosurgery is an important clinical tool for the treatment of small lesions in the brain, including benign conditions, malignant and localized metastatic tumors. A dosimetry study was performed for Elekta ‘Synergy S ’ as a dedicated Stereotactic radiosurgery unit, capable of generating circular radiation fields with diameters of 1-5 cm at isocentre using the BEAM/EGS4...

متن کامل

Evaluating Performance of Algorithms in Lung IMRT: A Comparison of Monte Carlo, Pencil Beam, Superposition, Fast Superposition and Convolution Algorithms

Background: Inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery.Objective: In the present study, the performance of five algorithms via Monte Carlo, Pencil Beam, Convolution, Fast Superposition and Superposition were evaluated in lung cancer Intensity Modulated Radiotherapy plannin...

متن کامل

An assessment of the Photon Contamination due to Bremsstrahlung Radiation in the Electron Beams of a NEPTUN 10PC Linac using a Monte Carlo Method

Introduction: In clinical electron beams, most of bremsstrahlung radiation is produced by various linac head structures. This bremsstrahlung radiation dose is influenced by the geometry and construction of every component of the linac treatment head structures. Thus, it can be expected that the amount of the contaminated photon dose due to bremsstrahlung radiation varies among different linacs,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014